A 67-year-old man with a 50 pack-year smoking history presents with persistent cough, hemoptysis, and 8-pound weight loss over two months. Vital signs show BP 138/86, HR 92, RR 18, temperature 37.2°C, SpO2 94% on room air. Chest CT reveals a central cavitary hilar mass. Serum calcium is 11.2 mg/dL (normal 8.5-10.5). He denies fever and has no lymphadenopathy on examination. Which of the following is the most likely diagnosis?
- A)Small cell carcinoma
- B)Squamous cell carcinomaGABARITO
- C)Adenocarcinoma
- D)Carcinoid tumor
- E)Mesothelioma
Explicação
Squamous cell carcinoma of the lung is strongly linked to smoking and usually arises centrally near the hilum. It often cavitates and can produce paraneoplastic hypercalcemia through PTH related peptide secretion. The combination of central cavitary lesion and... Ver explicação completa e trilha adaptativa →