A 19-year-old man with no prior neurological history experiences acute onset of paresthesias in both legs, progressive weakness, and urinary retention over 24 hours. MRI shows T2 hyperintensity spanning the entire thoracic spinal cord. CSF shows 250 WBC/μL (95% lymphocytes) and elevated protein. Which of the following findings would most strongly support a diagnosis of transverse myelitis rather than infection?
- A)Negative bacterial and viral cultures
- B)Presence of oligoclonal bandsGABARITO
- C)Gray matter involvement on MRI
- D)Elevated CSF glucose
- E)Absence of fever
Explicação
Oligoclonal bands in CSF indicate intrathecal immunoglobulin synthesis and are characteristic of demyelinating diseases like transverse myelitis. They reflect a specific inflammatory CNS response to demyelination and are more specific for demyelinating disease... Ver explicação completa e trilha adaptativa →