A 28-year-old woman at 8 weeks gestation presents for prenatal care. Her TSH is 6.2 mIU/L and free T4 is 0.9 ng/dL (low end of normal). She reports no symptoms. Thyroid peroxidase antibodies are positive. She has no prior thyroid disease. Which of the following is the most appropriate management?

  1. A)Monitor TSH every 2 months without treatment
  2. B)Refer for thyroid biopsy given antibody positivity
  3. C)Start levothyroxine 50 mcg dailyGABARITO
  4. D)Initiate iodine supplementation only
  5. E)Repeat TSH testing in one week; treat only if persistently elevated

Explicação

Subclinical hypothyroidism in pregnancy (elevated TSH with normal free T4) should be treated with levothyroxine to optimize fetal neurodevelopment. Current guidelines recommend treating pregnant women with TSH >2.5 mIU/L in the first trimester to prevent adver... Ver explicação completa e trilha adaptativa →

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