A 64-year-old woman with hypertension initiated a calcium channel blocker one month ago. She now presents with bilateral ankle edema, facial flushing, and headache. Vital signs show BP 128/76 mmHg, HR 72/min, RR 16/min, temperature 37°C, and SpO2 98% on room air. Laboratory studies reveal normal serum creatinine and urinalysis without proteinuria. There is no dyspnea or orthopnea. Which medication most likely caused these adverse effects through arteriolar vasodilation?
- A)Verapamil
- B)Hydrochlorothiazide
- C)Lisinopril
- D)AmlodipineGABARITO
- E)Metoprolol
Explicação
Amlodipine is a dihydropyridine calcium channel blocker that predominantly relaxes vascular smooth muscle. Peripheral edema, flushing, and headache are classic adverse effects due to precapillary arteriolar dilation. Ver explicação completa e trilha adaptativa →