A 68-year-old woman presents with fever (38.9°C), malaise, and knee swelling 10 days after prosthetic knee arthroplasty. Vital signs show HR 102/min, BP 138/88 mmHg, RR 18/min, SpO2 98% on room air. Joint aspirate reveals catalase-positive, coagulase-negative gram-positive cocci in clusters; WBC 18,500/μL with left shift. She denies recent antibiotic use. Which virulence factor most likely enabled this organism's persistence on the prosthetic surface?
- A)Protein A binding the Fc region of IgG
- B)Capsular antiphagocytic protein composed of D glutamate
- C)M protein inhibiting complement deposition
- D)Polysaccharide biofilm productionGABARITO
- E)Heat stable enterotoxin activating guanylate cyclase
Explicação
Staphylococcus epidermidis forms polysaccharide biofilms that adhere strongly to prosthetic material and protect the organism from host defenses and antibiotics. This makes it a classic cause of device related infections. Ver explicação completa e trilha adaptativa →