A 14 year old boy with sickle cell disease presents with fatigue, pallor, and lightheadedness for 3 days. He recently recovered from a mild febrile illness. Laboratory studies show hemoglobin 5.8 g per dL with a markedly decreased reticulocyte count. Which of the following infectious agents is the most likely cause of this patient’s current condition?
- A)Human herpesvirus 8
- B)Hepatitis B virus
- C)Parvovirus B19GABARITO
- D)Epstein Barr virus
- E)Coxsackie B virus
Explicação
Parvovirus B19 is correct. Patients with chronic hemolytic anemias such as sickle cell disease are susceptible to transient aplastic crisis when parvovirus infects erythroid precursors in the bone marrow. Severe anemia with reticulocytopenia is the key finding... Ver explicação completa e trilha adaptativa →