A 16-year-old male with sickle cell disease is hospitalized for a severe infection. His spleen has autosplenectomized, and he has had other minor infections in the past. His symptoms include fever, chills, cough, and chest pain. Bacteria from the patient's sputum are optochin-sensitive organisms with a positive quellung reaction. Which of the following is the most likely pathogen?

1. A)Escherichia coli
2. B)Streptococcus pneumoniaeGABARITO
3. C)Neisseria gonorrhoeae
4. D)Klebsiella pneumoniae
5. E)Haemophilus influenzae