A 59-year-old man presents with chronic steatorrhea, mild diabetes, and recurrent abdominal pain. Vital signs show BP 128/82 mmHg, HR 92/min, RR 16/min, temp 37.2°C, and SpO2 98%. Laboratory studies reveal fasting glucose 156 mg/dL and markedly elevated gastrin levels. Gastric pH is 1.5. Abdominal imaging demonstrates a 2-cm pancreatic neuroendocrine tumor; esophageal ulceration is notably absent. Which hormone is most likely being secreted in excess?
- A)VIP
- B)Gastrin
- C)SomatostatinGABARITO
- D)Glucagon
- E)Insulin
Explicação
Somatostatinomas inhibit release of many gastrointestinal and pancreatic hormones. The result is diabetes from reduced insulin, steatorrhea from reduced pancreatic secretion, gallstones from reduced cholecystokinin activity, and low gastric acid output. This i... Ver explicação completa e trilha adaptativa →