A 55-year-old man with cirrhosis presents with jaundice, ascites, and hepatic encephalopathy. Vital signs show BP 110/70, HR 92, RR 18, temp 37°C, SpO2 98%. Laboratory studies reveal elevated transaminases and INR 2.1. Ultrasound confirms cirrhosis with portal hypertension. Liver biopsy shows fibrotic regions with bridging fibrosis. In normal hepatic architecture adjacent to fibrotic areas, the pathologist identifies specialized macrophages within sinusoidal spaces. No malignancy is noted. These cells are most likely which of the following?
- A)Chief cells
- B)Kupffer cellsGABARITO
- C)Ito cells
- D)Centroacinar cells
- E)M cells
Explicação
Kupffer cells are the resident macrophages of the liver and line the hepatic sinusoids. They participate in phagocytosis of debris, microbes, and aged erythrocytes. The biopsy description of sinusoidal macrophages in hepatic tissue specifically identifies Kupf... Ver explicação completa e trilha adaptativa →