A 2-hour-old term male infant presents with severe cyanosis, shock, and metabolic acidosis. He has been dependent on prostaglandin E1 infusion since birth. Echocardiography shows a single arterial trunk arising from the heart with a large VSD and a single truncal valve. Which of the following associated anomalies is most likely present?

  1. A)Williams syndrome
  2. B)Marfan syndrome
  3. C)DiGeorge syndrome (22q11 deletion)GABARITO
  4. D)Noonan syndrome
  5. E)Down syndrome (Trisomy 21)

Explicação

Truncus arteriosus is associated with DiGeorge syndrome (22q11 deletion) in approximately 30-40% of cases. This syndrome also causes thymic hypoplasia, cleft palate, hypocalcemia, and immune deficiency. The truncus arteriosus classification system depends on t... Ver explicação completa e trilha adaptativa →

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