An 8-year-old unvaccinated boy presents with fever (38.9°C), sore throat, and progressive asymmetric flaccid paralysis of the left leg over 3 days. Vital signs show HR 102 bpm, BP 108/68 mmHg, RR 18/min, SpO2 98% on room air. Sensory examination is intact throughout. CSF analysis reveals lymphocytic pleocytosis with normal glucose. Deep tendon reflexes are diminished in the affected limb. Which of the following structures is most likely damaged?
- A)Posterior columns
- B)Anterior horn cellsGABARITO
- C)Dorsal root ganglia
- D)Basal ganglia
- E)Cerebellar Purkinje cells
Explicação
Poliovirus preferentially destroys anterior horn cells of the spinal cord, leading to asymmetric flaccid paralysis with preserved sensation. This LMN pattern helps distinguish it from sensory neuropathies or central motor disorders. Ver explicação completa e trilha adaptativa →