A 28-year-old man presents with recurrent infections of the lungs, liver, and bones, along with excessive inflammation manifesting as granulomas, gingivitis, aphthous ulcers, and seborrheic dermatitis. Vital signs show BP 118/76, HR 94, RR 18, temp 37.2°C, SpO2 98%. Laboratory studies reveal elevated inflammatory markers (ESR 42 mm/hr) and normal immunoglobulin levels. Chest X-ray shows granulomatous infiltrates. He denies recent antibiotic use. This patient most likely has a deficiency of an enzyme involved in which of the following processes?

  1. A)Peroxisomal fatty acid oxidation
  2. B)Nucleotide salvage
  3. C)Erythrocyte oxidative protection
  4. D)Enterocyte copper transport
  5. E)Neutrophil oxidative burstGABARITO

Explicação

The correct answer is C. Source: Kaplan USMLE Step 1 QBank — Biochemistry Test 2. Ver explicação completa e trilha adaptativa →

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