A 23-year-old woman with severe hirsutism, acne, and irregular menses presents with clinical hyperandrogenism. She is started on a medication that antagonizes aldosterone receptors while blocking androgen effects. Current vitals: BP 118/76 mmHg, HR 82/min, RR 16/min, temp 37°C. Laboratory studies show serum potassium 5.8 mEq/L (normal 3.5-5.0), normal creatinine, and elevated testosterone. She denies chest pain or palpitations. Which drug most likely caused her hyperkalemia?
- A)SpironolactoneGABARITO
- B)Clomiphene
- C)Eplerenone
- D)Finasteride
- E)Flutamide
Explicação
Spironolactone antagonizes aldosterone receptors and also has antiandrogen effects, making it useful in hirsutism and hyperaldosteronism. Hyperkalemia is a predictable consequence of its potassium sparing mineralocorticoid receptor blockade. Ver explicação completa e trilha adaptativa →