A 55-year-old man presents with progressive fatigue and recurrent bacterial infections. Vital signs: BP 128/82, HR 92, RR 16, Temp 37.2°C, SpO2 98%. Physical examination reveals moderate splenomegaly; lymphadenopathy is absent. CBC demonstrates pancytopenia (WBC 3.2K, Hgb 9.1, Plt 85K). Bone marrow aspiration yielded minimal material; biopsy reveals abnormal lymphocytes with characteristic hair-like cytoplasmic projections. Which histochemical stain is classically positive in this disorder?
- A)Vimentin only
- B)PSA
- C)Chromogranin
- D)TRAPGABARITO
- E)Desmin
Explicação
Hairy cell leukemia is classically tartrate resistant acid phosphatase positive. The dry tap, splenomegaly, pancytopenia, and cells with hair like projections are hallmark clues pointing to this diagnosis. Ver explicação completa e trilha adaptativa →