A 51-year-old man with acromegaly treated with transsphenoidal surgery presents with persistent symptoms. Vital signs: BP 148/92, HR 88, RR 16, Temp 98.6°F, SpO2 98%. Laboratory studies show elevated IGF-1 at 520 ng/mL (normal <200). MRI shows no residual pituitary adenoma. He denies headaches or vision changes. His endocrinologist prescribes a medication that antagonizes peripheral growth hormone receptors rather than suppressing pituitary hormone secretion. Which drug was most likely prescribed?
- A)PegvisomantGABARITO
- B)Leuprolide
- C)Clomiphene
- D)Octreotide
- E)Cabergoline
Explicação
Pegvisomant is a growth hormone receptor antagonist used in acromegaly when control remains inadequate. It lowers IGF 1 production in peripheral tissues even though circulating growth hormone levels may remain elevated. Ver explicação completa e trilha adaptativa →