A 61-year-old woman develops acute dyspnea, fever, and hypoxemia within 2 hours of plasma transfusion. Vital signs show BP 128/82 mmHg, HR 118 bpm, RR 28/min, temperature 38.5°C, and SpO2 82% on room air. Chest radiograph demonstrates bilateral pulmonary infiltrates. Jugular venous pressure is normal, and cardiac auscultation reveals no murmurs. Serum troponin is normal. Which diagnosis best explains her acute presentation?
- A)Warm autoimmune hemolytic anemia
- B)Acute hemolytic transfusion reaction
- C)Transfusion associated circulatory overload
- D)Febrile nonhemolytic transfusion reaction
- E)Transfusion related acute lung injuryGABARITO
Explicação
Transfusion related acute lung injury is correct. TRALI is caused by donor anti leukocyte antibodies that activate recipient neutrophils in the pulmonary microvasculature, producing noncardiogenic pulmonary edema. The normal jugular venous pressure helps disti... Ver explicação completa e trilha adaptativa →