A 67-year-old man with a history of hypertension and type 2 diabetes presents to the emergency department with acute onset of left-sided weakness and dysarthria. His wife reports symptom onset was approximately 2 hours ago while he was watching television. Vital signs are: BP 168/94 mmHg, HR 92/min regular, RR 18/min, temperature 37.2°C, SpO2 98% on room air. Physical examination reveals left arm and leg weakness (3/5), dysarthria, and no facial droop. Non-contrast CT of the head shows no acute hemorrhage. MRI brain with diffusion-weighted imaging demonstrates acute ischemic changes in the right middle cerebral artery territory. Cardiac examination reveals regular rate and rhythm with no murmurs; ECG shows normal sinus rhythm. Which of the following is the most appropriate next step in management?
- A)Initiate aspirin 325 mg orally and schedule carotid ultrasound for the following day
- B)Administer intravenous alteplase immediately and initiate aspirin after 24 hoursGABARITO
- C)Begin intravenous heparin for anticoagulation pending identification of embolic source
- D)Administer intravenous labetalol to achieve systolic BP <140 mmHg before thrombolysis
- E)Perform emergent transthoracic echocardiography and defer thrombolysis pending results
Explicação
This patient presents with acute ischemic stroke within the 4.5-hour thrombolytic window (symptom onset 2 hours prior). Non-contrast CT ruled out hemorrhage, and MRI confirms acute ischemic changes in MCA distribution. Intravenous alteplase (recombinant tissue... Ver explicação completa e trilha adaptativa →