A 73-year-old woman with severe osteoporosis presents with multiple vertebral compression fractures despite adequate calcium and vitamin D supplementation. Vital signs: BP 138/82, HR 76, RR 16, Temp 37°C. Laboratory studies show serum calcium 8.8 mg/dL and alkaline phosphatase 68 U/L. Bone density scan confirms T-score of –3.2. She denies recent falls or trauma. Her physician prescribes a daily injectable medication that, when given intermittently, increases osteoblast activity and bone formation. Which drug was most likely prescribed?
- A)Denosumab
- B)Raloxifene
- C)Calcitonin
- D)TeriparatideGABARITO
- E)Alendronate
Explicação
Teriparatide is a PTH analog that stimulates osteoblast activity when given intermittently, producing net bone formation. This anabolic mechanism distinguishes it from antiresorptive osteoporosis therapies such as bisphosphonates, denosumab, and calcitonin. Ver explicação completa e trilha adaptativa →