A 31-year-old woman presents with sudden-onset severe neck pain, fever (38.9°C), and malaise. Vital signs show tachycardia (HR 102/min) and tachypnea (RR 20/min). Laboratory studies reveal elevated inflammatory markers (ESR 68 mm/hr, CRP 12.5 mg/dL), TSH 6.2 mIU/L, and free T4 1.9 ng/dL (elevated). Thyroid ultrasound demonstrates heterogeneous echotexture with hypoechoic areas. She denies recent upper respiratory infection. Which of the following best describes the likely pathophysiology?
- A)Iodine-induced suppression of thyroid hormone synthesis
- B)Bacterial infection of thyroid parenchyma with abscess formation
- C)Autoimmune destruction of thyroid follicles with TSH receptor antibodies
- D)Thyroid peroxidase antibodies causing chronic inflammation
- E)Viral-mediated thyroid inflammation causing thyroid hormone release into circulationGABARITO
Explicação
Acute viral thyroiditis (subacute thyroiditis) presents with sudden neck pain, fever, and elevated markers. The elevated free T4 with elevated TSH indicates thyroid inflammation causing hormone release (destructive phase), not increased synthesis. This is foll... Ver explicação completa e trilha adaptativa →