A 36-year-old bird breeder presents with subacute dyspnea, fever (38.2°C), and malaise after cleaning bird cages. Vital signs show HR 102/min, RR 24/min, BP 118/76 mmHg, SpO2 91% on room air. Chest X-ray reveals diffuse micronodular infiltrates throughout both lung fields. Serum precipitins against avian proteins are positive; CBC shows normal WBC. Symptoms completely resolved after 2 weeks of antigen avoidance. Which immune response best characterizes this patient's condition?
- A)Type I hypersensitivity with mast cell degranulation
- B)Type III and IV hypersensitivity with immune complex and T-cell mediated inflammationGABARITO
- C)Direct cytotoxic T-cell mediated injury without antibodies
- D)Type II hypersensitivity with cytotoxic antibodies
- E)IgE-mediated anaphylaxis with airway edema
Explicação
Extrinsic allergic alveolitis (bird breeder's lung) results from Type III (immune complex/Arthus reaction) and Type IV (delayed-type/cell-mediated) hypersensitivity to inhaled organic antigens. Serum precipitins (antibodies) indicate immune complex formation, ... Ver explicação completa e trilha adaptativa →