A 62-year-old man with a 40-pack-year smoking history presents with progressive dyspnea and a nonproductive cough over 8 months. He reports no occupational exposures, recent infections, or immunosuppressive medications. Vital signs show oxygen saturation of 88% on room air. High-resolution CT of the chest demonstrates bilateral lower lobe predominant reticular opacities with traction bronchiectasis and minimal ground-glass infiltrates. Pulmonary function tests reveal FVC 65% predicted, FEV1 62% predicted, FEV1/FVC ratio 0.78, and DLCO 45% predicted. Which of the following is the most likely diagnosis?
- A)Acute interstitial pneumonia
- B)Nonspecific interstitial pneumonia
- C)Respiratory bronchiolitis-associated interstitial lung disease
- D)Desquamative interstitial pneumonia
- E)Usual interstitial pneumoniaGABARITO
Explicação
Usual interstitial pneumonia (UIP) is the most likely diagnosis. The clinical presentation of progressive dyspnea and dry cough over months in a long-term smoker, combined with the HRCT findings of bilateral lower lobe-predominant reticular opacities with trac... Ver explicação completa e trilha adaptativa →