A 19-year-old college student presents to the emergency department with fever (39.8°C), hypotension (BP 78/52 mmHg), tachycardia (HR 128/min), and a rapidly progressive petechial rash. Despite aggressive fluid resuscitation and vasopressors, he remains in septic shock. Laboratory studies reveal thrombocytopenia (platelets 45,000/μL) and elevated lactate (4.2 mmol/L). CT abdomen shows bilateral adrenal hemorrhage. He denies recent antibiotic use. Which organism is most classically associated with this presentation?
- A)Neisseria meningitidisGABARITO
- B)Haemophilus influenzae
- C)Pseudomonas aeruginosa
- D)Streptococcus pneumoniae
- E)Staphylococcus aureus
Explicação
Waterhouse Friderichsen syndrome is acute adrenal insufficiency due to bilateral adrenal hemorrhage, classically triggered by meningococcemia. Fulminant septic shock with petechiae and disseminated intravascular coagulation is the classic presentation. Loss of... Ver explicação completa e trilha adaptativa →