A 28-year-old woman of Mediterranean descent presents with mild anemia (hemoglobin 10.2 g/dL), microcytia (MCV 72 fL), and normal iron stores. Serum ferritin is elevated at 145 ng/mL (normal <150). Hemoglobin electrophoresis shows elevated hemoglobin A2 (3.8%) and normal fetal hemoglobin. Which of the following is the most likely diagnosis?

  1. A)Sickle cell trait
  2. B)β-Thalassemia traitGABARITO
  3. C)Iron deficiency anemia
  4. D)Hemoglobin E disease
  5. E)α-Thalassemia trait

Explicação

β-Thalassemia trait presents with mild microcytic anemia, normal or elevated iron stores, and elevated HbA2 (>3.5%) on electrophoresis. Normal HbF and Mediterranean ethnicity support this diagnosis. Ver explicação completa e trilha adaptativa →

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