A 68-year-old retired construction worker presents with 6 months of progressive exertional dyspnea. Vital signs show BP 138/82, HR 98, RR 22, SpO2 88% on room air. Pulmonary function tests demonstrate restrictive pattern with FVC 62% predicted. High-resolution CT chest shows upper-lobe predominant fibrosis. Lung biopsy reveals golden-brown beaded rods within macrophages staining positive for iron. No fever or constitutional symptoms. Which diagnosis best explains these findings?
- A)Idiopathic pulmonary fibrosis
- B)Silicosis
- C)Coal workers pneumoconiosis
- D)Sarcoidosis
- E)AsbestosisGABARITO
Explicação
Asbestosis is correct. Iron coated asbestos fibers form ferruginous bodies, a classic pathologic clue in a patient with occupational exposure and restrictive physiology. The associated interstitial fibrosis typically involves the lower lobes and may coexist wi... Ver explicação completa e trilha adaptativa →