A 53-year-old man with acute myelogenous leukemia undergoing chemotherapy presents with pleuritic chest pain and hemoptysis during severe neutropenia (WBC 0.8 K/μL). Vital signs show BP 128/82, HR 102, RR 22, Temp 38.2°C, SpO2 94% on room air. Chest CT reveals multiple nodular lesions with surrounding ground-glass opacity. Lung biopsy demonstrates septate hyphae branching at acute angles. He denies recent antifungal prophylaxis. Which organism is most likely responsible?
- A)Blastomyces dermatitidis
- B)Candida albicans
- C)Mucor species
- D)Cryptococcus neoformans
- E)Aspergillus fumigatusGABARITO
Explicação
Aspergillus causes invasive pulmonary disease in neutropenic patients and is identified by septate hyphae with acute angle branching. Angioinvasion can lead to hemoptysis and characteristic nodular lesions in immunocompromised hosts. Ver explicação completa e trilha adaptativa →