A 29-year-old woman with a 2-year history of infertility due to anovulation presents wanting to conceive. Vital signs are stable (BP 118/76, HR 78, RR 14, Temp 37°C). Serum FSH is 3.2 mIU/mL (low-normal) and LH is 2.8 mIU/mL. Thyroid function tests are normal. She takes no hormonal contraceptives. Her physician prescribes a drug blocking estrogen feedback at the hypothalamus to increase GnRH, FSH, and LH secretion. Which drug was most likely prescribed?

  1. A)ClomipheneGABARITO
  2. B)Tamoxifen
  3. C)Leuprolide
  4. D)Raloxifene
  5. E)Mifepristone

Explicação

Clomiphene is a selective estrogen receptor modulator that blocks estrogen feedback at the hypothalamus and pituitary, increasing GnRH pulsatility and gonadotropin release. It is commonly used to induce ovulation in anovulatory infertility. Ver explicação completa e trilha adaptativa →

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