A 6-year-old boy with Down syndrome presents to the clinic with progressive dyspnea on exertion over the past 6 months. His mother reports he can no longer keep up with peers during play. Vital signs: HR 115 bpm, RR 30, BP 92/58, SpO2 91% on room air. Physical examination reveals a hyperdynamic precordium with prominent right ventricular heave, single loud S2 with accentuated pulmonary component, and a holosystolic murmur best heard at the left lower sternal border. No cyanosis is noted. Chest X-ray shows increased pulmonary vascular markings, pulmonary artery prominence, and right atrial enlargement. Which of the following is the most likely diagnosis?

  1. A)Atrioventricular septal defect with early pulmonary hypertensionGABARITO
  2. B)Tetralogy of Fallot with progressive right ventricular outflow tract obstruction
  3. C)Atrioventricular septal defect with established Eisenmenger syndrome
  4. D)Partial anomalous pulmonary venous return to the superior vena cava
  5. E)Patent foramen ovale with secundum-type atrial septal defect

Explicação

Atrioventricular septal defect (AVSD) is the most common cardiac lesion in Down syndrome (30-40% of cardiac cases). The clinical presentation shows accentuated pulmonary component of S2, holosystolic murmur (AV valve regurgitation), right ventricular heave, an... Ver explicação completa e trilha adaptativa →

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