A 69-year-old postmenopausal woman with osteoporosis (T-score −2.8 on DEXA scan) and a serum calcium of 9.4 mg/dL presents with BP 128/76, HR 72, RR 14, and normal temperature. She has a history of one fragility fracture of the left wrist two years ago. She is started on a weekly oral drug that binds hydroxyapatite and inhibits osteoclast-mediated bone resorption. She reports no heartburn or dysphagia. The physician instructs her to remain upright for 30 minutes after administration with a full glass of water to reduce esophageal injury risk. Which drug was most likely prescribed?
- A)Raloxifene
- B)Cinacalcet
- C)Teriparatide
- D)AlendronateGABARITO
- E)Calcitonin
Explicação
Alendronate is a bisphosphonate that inhibits osteoclast mediated bone resorption. Esophagitis is a classic adverse effect, so patients are instructed to take it with water and remain upright afterward. Ver explicação completa e trilha adaptativa →