A 47-year-old woman with type 2 diabetes presents with 4 months of large-volume watery diarrhea persisting during fasting. Vital signs show BP 118/76, HR 102, RR 18, temp 37°C. Labs reveal serum potassium 2.8 mEq/L and gastric pH 6.2. She reports progressive proximal muscle weakness and denies recent antibiotic use. Current medications include metformin and lisinopril. Which tumor best explains this clinical syndrome?
- A)Somatostatinoma
- B)VIPomaGABARITO
- C)Zollinger Ellison syndrome
- D)Insulinoma
- E)Glucagonoma
Explicação
VIPoma causes watery diarrhea, hypokalemia, and achlorhydria, often summarized as WDHA syndrome. Vasoactive intestinal peptide stimulates intestinal secretion and inhibits gastric acid secretion. The diarrhea typically persists despite fasting because it is se... Ver explicação completa e trilha adaptativa →