A 37-year-old woman undergoes MRI for suspected MS and is found to have multiple brain T2 lesions, but only 1 lesion shows gadolinium enhancement. Spine MRI is normal. She reports mild cognitive difficulties but no recent relapses. Which of the following supports a diagnosis of MS over other demyelinating conditions?

  1. A)Cognitive symptoms are pathognomonic for MS
  2. B)The presence of gadolinium enhancement indicates acute demyelination specific to MS
  3. C)Evidence of dissemination in space with both enhancing and non-enhancing lesions of different agesGABARITO
  4. D)Normal spine MRI confirms that this is MS rather than myelitis-associated disease
  5. E)Absence of spinal cord involvement excludes other demyelinating diseases

Explicação

MS diagnostic criteria emphasize dissemination in space (lesions in different CNS regions) and time (lesions of different ages/enhancement patterns). The combination of multiple T2 lesions with only some enhancing gadolinium indicates lesions of different ages... Ver explicação completa e trilha adaptativa →

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