A 58-year-old man with a 40 pack-year smoking history presents with a 3-month history of productive cough and occasional hemoptysis. Vital signs are stable and oxygen saturation is 98% on room air. Chest CT reveals a 3-cm left upper lobe nodule suspicious for malignancy. A prospective cohort study follows 10,000 smokers and 10,000 non-smokers for 10 years. Over this period, lung cancer develops in 400 smokers and 20 non-smokers. Which of the following best represents the relative risk of lung cancer in smokers compared to non-smokers?
- A)5.0
- B)10.0
- C)20.0GABARITO
- D)40.0
- E)200.0
Explicação
Relative risk (RR) is calculated as the ratio of incidence in the exposed group to incidence in the unexposed group. Incidence in smokers = 400/10,000 = 0.04 (or 4%). Incidence in non-smokers = 20/10,000 = 0.002 (or 0.2%). RR = 0.04/0.002 = 20.0. This means sm... Ver explicação completa e trilha adaptativa →