A 39-year-old man with severe asthma presents with fever (38.5°C), sinus pain, and hemoptysis. Vital signs show BP 128/82 mmHg, HR 102/min, RR 22/min, SpO2 94% on room air. He reports neuropathic tingling in his feet. Laboratory studies reveal marked eosinophilia (8,500/μL) and elevated IgE levels. Chest X-ray shows pulmonary infiltrates. He denies recent infections or travel. Which of the following is the most likely diagnosis?
- A)Microscopic polyangiitis
- B)Pulmonary alveolar proteinosis
- C)Eosinophilic granulomatosis with polyangiitisGABARITO
- D)Goodpasture syndrome
- E)Idiopathic pulmonary fibrosis
Explicação
Eosinophilic granulomatosis with polyangiitis is correct. This small vessel vasculitis is associated with asthma, eosinophilia, sinus disease, pulmonary infiltrates, and systemic manifestations such as neuropathy. The strong atopic airway history distinguishes... Ver explicação completa e trilha adaptativa →