A 60-year-old man with type 2 diabetes mellitus and heart failure presents with fatigue. Vitals: BP 128/76 mmHg, HR 92/min, RR 16/min, Temp 37°C, SpO2 98% on room air. Recent fasting glucose is 156 mg/dL; HbA1c is 7.8%. He denies polyuria. He is started on a medication that lowers blood glucose by increasing urinary glucose excretion via inhibition of proximal tubule reabsorption. Which drug most likely has this mechanism of action?
- A)Glipizide
- B)Liraglutide
- C)Metformin
- D)EmpagliflozinGABARITO
- E)Sitagliptin
Explicação
SGLT2 inhibitors such as empagliflozin block sodium glucose cotransport in the proximal tubule, increasing glucosuria. Ver explicação completa e trilha adaptativa →