A 27-year-old man presents with recurrent bloody diarrhea and urgency. Vital signs show HR 92/min, BP 118/76 mmHg, RR 16/min, Temp 37.2°C. Colonoscopy reveals continuous mucosal inflammation starting in the rectum extending through the sigmoid colon. Laboratory studies show hemoglobin 11.2 g/dL and elevated CRP at 8.5 mg/L. He denies arthralgia or eye symptoms. Which extraintestinal manifestation is most strongly associated with this disease?
- A)Primary sclerosing cholangitisGABARITO
- B)Fistula formation and transmural inflammation
- C)Noncaseating granulomas in the terminal ileum
- D)Oxalate kidney stones from fat malabsorption
- E)Mouth ulcers with skip lesions
Explicação
Ulcerative colitis is a mucosal inflammatory disease limited to the colon that characteristically begins in the rectum and extends continuously. It is associated with p-ANCA positivity and primary sclerosing cholangitis, a cholestatic disease of intrahepatic a... Ver explicação completa e trilha adaptativa →