A 25-year-old man with a history of intravenous drug use is found unresponsive with shallow breathing (RR 8/min), bradycardia (HR 52/min), and pinpoint pupils. Vital signs show BP 88/56 mmHg, temperature 35.2°C, and SpO2 78% on room air. Physical examination reveals track marks on both forearms and fresh needle puncture wounds. Arterial blood gas shows respiratory acidosis with pH 7.22 and PaCO2 68 mmHg. No evidence of trauma or focal neurological deficits is noted. Which medication most appropriately reverses the life-threatening effects of his suspected overdose?
- A)Flumazenil
- B)NaloxoneGABARITO
- C)Fomepizole
- D)Atropine
- E)Pralidoxime
Explicação
Naloxone is a competitive opioid receptor antagonist that rapidly reverses respiratory depression and central nervous system depression in opioid overdose. Miosis and hypoventilation in an injection drug user strongly support this diagnosis. Ver explicação completa e trilha adaptativa →