A 28-year-old male spelunker from Ohio presents one week after exploring bat-infested caves with fever (38.9°C), productive cough, and pleuritic chest pain. Vital signs show BP 128/82, HR 102, RR 20, SpO2 94% on room air. Chest X-ray demonstrates patchy alveolar infiltrates with hilar lymphadenopathy. Laboratory studies reveal elevated transaminases (AST 78 U/L). He denies hemoptysis. Which organism most likely caused this infection?

  1. A)Histoplasma capsulatumGABARITO
  2. B)Coccidioides immitis
  3. C)Tuberculosis
  4. D)Pneumocystis jirovecii pneumonia
  5. E)Blastomyces dermatitidis

Explicação

Histoplasma capsulatum is correct. Exposure to bat droppings in the Ohio River valley is a classic clue, and histoplasmosis can present with pulmonary infiltrates and hilar adenopathy. The organism resides in macrophages as small oval yeasts. Ver explicação completa e trilha adaptativa →

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