A 68-year-old man with no family history presents with asymmetric akinesia, rigidity on the more affected side, and progressive cortical sensory loss. He develops apraxia and alien hand phenomenon on the less affected side. Brain MRI shows asymmetric cortical atrophy of the motor cortex. Which of the following is the most likely diagnosis?
- A)Parkinson disease
- B)Asymmetric stroke
- C)Multiple system atrophy
- D)Corticobasal degenerationGABARITO
- E)Progressive supranuclear palsy
Explicação
Corticobasal degeneration (CBD) is a tauopathy presenting with asymmetric cortical and basal ganglia dysfunction. Key features include asymmetric akinesia-rigidity, cortical sensory loss, apraxia, and alien hand phenomenon. Brain MRI shows asymmetric cortical ... Ver explicação completa e trilha adaptativa →