A 55-year-old man with poorly controlled diabetes mellitus presents with fever (39.2°C), tachycardia (110 bpm), and black necrotic tissue on the hard palate extending into the right orbit. He denies rhinorrhea. Labs show blood glucose 520 mg/dL, arterial pH 7.18, and negative blood cultures. CT reveals opacification of the maxillary sinus. Palatal biopsy demonstrates wide, ribbon-like, non-septate hyphae with right-angle branching. What is the most likely diagnosis?
- A)Candidiasis
- B)Aspergillosis
- C)Cryptococcosis
- D)Histoplasmosis
- E)MucormycosisGABARITO
Explicação
Mucormycosis (Rhizopus, Mucor) is characterized by wide, non-septate (pauciseptate) hyphae branching at right angles. It is associated with diabetic ketoacidosis and is angioinvasive, causing tissue necrosis. Ver explicação completa e trilha adaptativa →