A 49-year-old woman with a 12-year history of obesity and type 2 diabetes presents to her primary care physician for a routine follow-up. Her current medications include metformin 1000 mg twice daily, but her glycemic control remains suboptimal. Her BMI is 34 kg/m², blood pressure is 128/82 mmHg, and fasting plasma glucose is 187 mg/dL. Her most recent HbA1c is 8.4%. Physical examination reveals acanthosis nigricans at the nape of the neck and mild central adiposity. She expresses strong interest in a medication that improves glycemic control while also promoting weight loss. Her physician prescribes a once-weekly injectable drug that increases glucose-dependent insulin secretion, decreases glucagon release, and delays gastric emptying. Which of the following medications was most likely prescribed?

  1. A)Insulin glargine
  2. B)Miglitol
  3. C)Glyburide
  4. D)SemaglutideGABARITO
  5. E)Metformin

Explicação

Semaglutide is a GLP-1 receptor agonist that enhances glucose dependent insulin secretion, suppresses glucagon, slows gastric emptying, and can promote meaningful weight loss. Those features make it attractive in patients with type 2 diabetes and obesity. The ... Ver explicação completa e trilha adaptativa →

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