A 49-year-old woman with a 12-year history of obesity and type 2 diabetes presents to her primary care physician for a routine follow-up. Her current medications include metformin 1000 mg twice daily, but her glycemic control remains suboptimal. Her BMI is 34 kg/m², blood pressure is 128/82 mmHg, and fasting plasma glucose is 187 mg/dL. Her most recent HbA1c is 8.4%. Physical examination reveals acanthosis nigricans at the nape of the neck and mild central adiposity. She expresses strong interest in a medication that improves glycemic control while also promoting weight loss. Her physician prescribes a once-weekly injectable drug that increases glucose-dependent insulin secretion, decreases glucagon release, and delays gastric emptying. Which of the following medications was most likely prescribed?
- A)Insulin glargine
- B)Miglitol
- C)Glyburide
- D)SemaglutideGABARITO
- E)Metformin
Explicação
Semaglutide is a GLP-1 receptor agonist that enhances glucose dependent insulin secretion, suppresses glucagon, slows gastric emptying, and can promote meaningful weight loss. Those features make it attractive in patients with type 2 diabetes and obesity. The ... Ver explicação completa e trilha adaptativa →