A 34-year-old woman with a history of hypertension managed with a daily oral beta-blocker is scheduled for a minor outpatient procedure. Prior to the procedure, she receives an intravenous sedative agent. Her vital signs are stable at a blood pressure of 118/74 mmHg, heart rate of 62 beats per minute, respiratory rate of 14 breaths per minute, and oxygen saturation of 99% on room air. The drug administered rapidly leaves the plasma and accumulates widely in adipose tissue and other peripheral organs. A pharmacologist reviewing the case notes that only a small fraction of the administered dose remains in the intravascular compartment after equilibration, requiring careful dosing adjustments in obese patients. Which of the following best describes this drug?

1. A)Poor tissue binding with a small extracellular fluid distribution
2. B)Rapidly renally excreted with zero order elimination
3. C)Highly protein bound with a very low volume of distribution
4. D)Highly lipophilic with a large volume of distributionGABARITO
5. E)Large and strongly charged with confinement to plasma