A 26 year old man comes to the emergency department with hemoptysis, fatigue, and decreased urine output for 5 days. Examination shows mild bibasilar crackles and hypertension. Serum creatinine is markedly elevated. Urinalysis reveals hematuria with red cell casts. Kidney biopsy shows crescent formation, and immunofluorescence demonstrates a linear pattern of IgG deposition along the glomerular basement membrane. Which of the following is the most likely diagnosis?
- A)Poststreptococcal glomerulonephritis
- B)Goodpasture syndromeGABARITO
- C)Granulomatosis with polyangiitis
- D)Minimal change disease
- E)Membranous nephropathy
Explicação
Goodpasture syndrome is correct. Anti basement membrane antibodies against type IV collagen in the glomerular and alveolar basement membranes cause rapidly progressive glomerulonephritis with pulmonary hemorrhage. The linear immunofluorescence pattern and hemo... Ver explicação completa e trilha adaptativa →