A 63-year-old woman presents with recurrent nephrolithiasis and fatigue. Vital signs: BP 138/88 mmHg, HR 92/min, RR 14/min, temperature 37.2°C. Serum calcium is 11.2 mg/dL (normal 8.5-10.2), with PTH elevated at 145 pg/mL. Urinalysis shows no hematuria. CT imaging reveals a 1.2-cm left parathyroid adenoma. Parathyroid exploration is performed. The normal parathyroid tissue not involved by the adenoma would most likely demonstrate which of the following histologic features?
- A)Islets surrounded by pancreatic acini
- B)Chromaffin cells derived from neural crest
- C)Colloid-filled follicles lined by cuboidal epithelium
- D)Cords of chief cells with scattered oxyphil cellsGABARITO
- E)Zona fasciculata with lipid-rich cells
Explicação
Normal parathyroid tissue is composed mainly of chief cells arranged in cords, with scattered oxyphil cells that increase with age. Chief cells secrete parathyroid hormone, which explains the hypercalcemia and nephrolithiasis in parathyroid adenoma. The absenc... Ver explicação completa e trilha adaptativa →