A 55-year-old man with type 2 diabetes and poor glucose control presents with a black, necrotic lesion on his hard palate that extends into surrounding tissues. He reports rapid onset of facial pain and swelling over 2 days. Biopsy shows broad, non-septate hyphae. Which of the following is the most important immediate therapeutic intervention?
- A)IV fluconazole monotherapy
- B)Aggressive surgical debridement with IV amphotericin BGABARITO
- C)Oral itraconazole with insulin adjustment
- D)Topical antifungal cream and glucose control
- E)Observation with supportive care pending culture results
Explicação
Mucormycosis (Rhizopus species) presents with rapid necrotic tissue invasion, particularly in diabetics. The broad, non-septate hyphae are pathognomonic. This is a medical emergency requiring aggressive surgical debridement of all necrotic tissue combined with... Ver explicação completa e trilha adaptativa →