A 22-year-old woman at 8 weeks gestation presents to clinic with fever (38.8°C), arthralgias in her hands and feet, and a maculopapular rash that began on her face 2 days ago and is now spreading to her trunk and extremities. She recently returned from a 2-week volunteer trip to Brazil. Physical examination is otherwise unremarkable; she denies headache, meningeal signs, or neurologic symptoms. Laboratory testing shows positive Zika virus IgM antibodies and negative dengue IgM. Ultrasound shows appropriate fetal size for gestational age with normal anatomy. Which of the following is the most likely serious fetal complication she should be counseled about?

1. A)Neonatal varicella-zoster infection with disseminated disease
2. B)Congenital cytomegalovirus with hydrops fetalis and hepatosplenomegaly
3. C)Congenital Zika syndrome with microcephaly and intracranial calcificationsGABARITO
4. D)Congenital rubella syndrome with patent ductus arteriosus and deafness
5. E)Congenital herpes simplex virus with disseminated skin, eye, and mouth disease