A 23-year-old woman with a 2-year history of abdominal pain and nonbloody diarrhea presents with 8-pound weight loss. Vital signs: BP 118/76, HR 88, RR 16, Temp 37.2°C, SpO2 98%. Laboratory studies show hemoglobin 11.2 g/dL and elevated inflammatory markers. Colonoscopy reveals skip lesions with patchy inflammation and normal intervening mucosa. Biopsy demonstrates transmural inflammation with noncaseating granulomas. No rectal bleeding is noted. Which complication is most likely to develop in this patient?

  1. A)Disease limited to the rectum
  2. B)Fistula formationGABARITO
  3. C)Toxic megacolon due to superficial mucosal inflammation
  4. D)Primary sclerosing cholangitis
  5. E)Shortened, featureless colon with lead pipe appearance

Explicação

Crohn disease is a transmural inflammatory bowel disease with skip lesions and noncaseating granulomas. Because the inflammation extends through the bowel wall, fistulas, strictures, and abscesses are common complications. Ver explicação completa e trilha adaptativa →

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