A 28-year-old male comes to the physician because of intermittent right upper quadrant pain that extends to the inferior tip of his scapula. Laboratory studies show mild anemia, with erythrocytes of relatively normal shape that appear normocytic and normochromic. Laparoscopic cholecystectomy shows an accumulation of bilirubin diglucuronide. A defect in which of the following metabolic pathways is most likely in this patient?

1. A)Heme degradation
2. B)Urea synthesis
3. C)Homocysteine metabolism
4. D)Glycogen synthesis
5. E)Hexose monophosphate shuntGABARITO