A 7-year-old boy is brought to the emergency department after ingesting unknown berries from a garden 2 hours ago. He is agitated and hallucinating, with flushed skin, temperature 39.2°C, heart rate 128/min, and blood pressure 142/88 mmHg. Physical examination reveals widely dilated pupils, dry mucous membranes, urinary retention, and absent bowel sounds. Serum electrolytes are normal. Which of the following drugs is most appropriate if supportive care is insufficient and no contraindications are present?
- A)PhysostigmineGABARITO
- B)Propranolol
- C)Pralidoxime
- D)Pilocarpine eye drops only
- E)Atropine
Explicação
This child has an anticholinergic toxidrome with hyperthermia, mydriasis, dry skin, agitation, and urinary retention. Physostigmine is a reversible acetylcholinesterase inhibitor that crosses the blood brain barrier and can reverse both central and peripheral ... Ver explicação completa e trilha adaptativa →