A 5-year-old girl develops bloody diarrhea after consuming undercooked beef at a picnic. Three days later, she presents with pallor, decreased urine output, and petechiae. Vital signs show BP 95/62 mmHg, HR 118/min, RR 22/min, and temperature 37.2°C. Laboratory studies reveal hemoglobin 7.2 g/dL with schistocytes on blood smear, platelet count 45,000/μL, and serum creatinine 2.8 mg/dL. Urinalysis shows no proteinuria. Which of the following is the most likely diagnosis?

  1. A)Minimal change disease
  2. B)Goodpasture syndrome
  3. C)Hemolytic uremic syndromeGABARITO
  4. D)Acute interstitial nephritis
  5. E)Disseminated intravascular coagulation

Explicação

Hemolytic uremic syndrome is correct. Shiga toxin associated endothelial injury triggers a thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury, especially in children after bloody diarrhea. R... Ver explicação completa e trilha adaptativa →

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