A 3-month-old male with trisomy 21 presents with poor feeding and failure to thrive. Vital signs show HR 156 bpm, RR 48/min, BP 82/56 mmHg, and SpO2 94% on room air. Physical examination reveals a systolic murmur at the left lower sternal border. Chest X-ray demonstrates cardiomegaly with pulmonary congestion. Echocardiography reveals abnormal fusion of the atrioventricular septal region with a common atrioventricular valve. Lung auscultation shows no rales. Which of the following is the most likely diagnosis?
- A)Tetralogy of Fallot
- B)Endocardial cushion defectGABARITO
- C)Ebstein anomaly
- D)Patent ductus arteriosus
- E)Coarctation of the aorta
Explicação
Endocardial cushion defect is correct. Down syndrome is strongly associated with atrioventricular septal defects caused by abnormal fusion of the superior and inferior endocardial cushions. These lesions disrupt formation of the lower atrial septum, upper vent... Ver explicação completa e trilha adaptativa →