A 70-year-old man presents to his primary care physician with a 6-month history of urinary hesitancy, weak urinary stream, and nocturia occurring three to four times per night. He reports no dysuria, hematuria, or fever. His past medical history is significant for well-controlled type 2 diabetes and mild osteoarthritis. Vital signs reveal a blood pressure of 128/78 mmHg and a heart rate of 72 beats per minute. Digital rectal examination reveals a smooth, symmetrically enlarged prostate estimated at 40 grams without nodularity or tenderness. Serum PSA is 2.1 ng/mL. Urinalysis is unremarkable. He is started on a medication that selectively blocks alpha-1A receptors in prostatic smooth muscle and therefore has minimal effect on systemic blood pressure. Which of the following drugs was most likely prescribed?
- A)TamsulosinGABARITO
- B)Finasteride
- C)Mirabegron
- D)Phenoxybenzamine
- E)Prazosin
Explicação
Tamsulosin selectively blocks alpha 1A receptors that predominate in the prostate and bladder neck. This improves urinary outflow in benign prostatic hyperplasia with less orthostatic hypotension than nonselective alpha 1 blockers. Ver explicação completa e trilha adaptativa →